Antares Pharma has received approval from the FDA for Otrexup (methotrexate) injection. Otrexup is the first FDA-approved subcutaneous (SC) methotrexate (MTX) for once weekly self-administration with an easy-to-use, single-dose, disposable auto injector. Otrexup is indicated for adults with severe active rheumatoid arthritis (RA) who have had an insufficient therapeutic response to or are intolerant of an adequate trial of first line therapy including full dose non-steroidal anti-inflammatory ag...